Output for HD editing

What are the best settings to export from Toon Boom for minimum filesize without any loss of quality?

The camera is 1920x1080 and I’ll be importing into Premiere to combine with HD video.

Thanks for your help!

Working with High-Definition-Video (1920 x 1080) involves always big file-sizes,
depending on complexity of footage and projects…

Be aware HD is roughly 4-times the size of Standard-Definition…
Make sure you have a high-speed external drive, or better, a high-speed-drive-array
with lots of storage space…

From Toon Boom Studio export your projects (1920 x 1080) either as QuickTime Movie,
e.g. Animation / AIC, ProRes (Mac) etc.
Or, as Image Sequence (PSD, PND, TGA, TIFF) etc…
Either, assemble with QuickTime (or else)…
Or import those sequences directly into your Video Editor…

Exporting from your Video Editor to your chosen delivery-format…
e.g. Your own Website, YouTube etc…
This should be the last and only stage to apply the necessary compression…

Regards
Nolan